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Root to Rx
Oliver Buchannon
Justin Yamashita

Benchtop, site, CRO. Three levels of basic and clinical research, explained without spin

Cancer

+1

Root to Rx Issue 007 - Plain Talk: The Trial That Stopped Itself

May 28, 2026

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7 min read

Root to Rx Issue 007 - Plain Talk: The Trial That Stopped Itself

The FDA approved Gleevec in 71 days. Here is what that actually means.

Justin Yamashita
Justin Yamashita

The Root Room

+2

Root to Rx Issue 007 - Web Companion: The Root Room and The Informed

May 28, 2026

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9 min read

Root to Rx Issue 007 - Web Companion: The Root Room and The Informed

Debby's friend Linda has CML. This time, she read to find out if her friend would be okay.

Justin Yamashita
Justin Yamashita

Junior Researcher

Sprout the Jr. Researcher is here

May 23, 2026

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1 min read

Sprout the Jr. Researcher is here

A free printable coloring book for curious kids ages 5-9

Justin Yamashita
Justin Yamashita

Cancer

+1

Root to Rx Issue 006 - Plain Talk: Breaking the Switch

May 21, 2026

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7 min read

Root to Rx Issue 006 - Plain Talk: Breaking the Switch

Brian Druker's decade in the lab, and the drug that almost never happened

Justin Yamashita
Justin Yamashita

The Root Room

+2

Root to Rx Issue 006 - Web Companion: The Root Room and The Informed

May 21, 2026

•

12 min read

Root to Rx Issue 006 - Web Companion: The Root Room and The Informed

The 6 years, the 53 of 54, and the doubling-time insight. Web companion to Issue 006 Plain Talk.

Justin Yamashita
Justin Yamashita

The Root Room

+2

Root to Rx Issue 005 - Web Companion: The Root Room and The Informed

May 14, 2026

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12 min read

Root to Rx Issue 005 - Web Companion: The Root Room and The Informed

The chromosome nobody believed for 13 years

Justin Yamashita
Justin Yamashita

Cancer

+1

Root to Rx Issue 005 - Plain Talk: The chromosome nobody believed for 13 years

May 14, 2026

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9 min read

Root to Rx Issue 005 - Plain Talk: The chromosome nobody believed for 13 years

Plain Talk · The Gleevec story, Part 1 of 4

Justin Yamashita
Justin Yamashita

The Root Room

+1

Root to Rx Issue 004 - Web Companion: The Root Room and The Informed

May 7, 2026

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14 min read

Root to Rx Issue 004 - Web Companion: The Root Room and The Informed

Web only. Debby's first encounter with the Skeptic's Toolkit, plus the full regulatory and statistical mechanics behind Plain Talk.

Justin Yamashita
Justin Yamashita

Plain Talk

Root to Rx Issue 004 - Plain Talk: From Molecule to Medicine: The Drug Development Pipeline

May 7, 2026

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13 min read

Root to Rx Issue 004 - Plain Talk: From Molecule to Medicine: The Drug Development Pipeline

Inside the system that turns 1 in 10,000 compounds into a medicine.

Justin Yamashita
Justin Yamashita

Vaccines

+1

Root to Rx Issue 003b - Vaccine Myths, Set Straight

May 1, 2026

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17 min read

Root to Rx Issue 003b - Vaccine Myths, Set Straight

Eight claims. One evidence base. Sprouting a toolkit for everyone.

Justin Yamashita
Justin Yamashita

Vaccines

+2

Root to Rx Issue 003a - The mRNA Research Timeline

Apr 30, 2026

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18 min read

Root to Rx Issue 003a - The mRNA Research Timeline

Four Scientists. Four Decades. One Platform. How mRNA Was Actually Ready.

Justin Yamashita
Justin Yamashita

Vaccines

+2

Root to Rx Issue 002 -  How Did They Build a COVID Vaccine in Less Than a Year?

Apr 23, 2026

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16 min read

Root to Rx Issue 002 - How Did They Build a COVID Vaccine in Less Than a Year?

Operation Warp Speed, explained. No shortcuts. No skipped steps. The full story. | Root to Rx Issue 002

Justin Yamashita
Justin Yamashita

Vaccines

+2

Root to Rx Issue 001 - Why Your Distrust Is Rational (And What Changed)

Apr 13, 2026

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7 min read

Root to Rx Issue 001 - Why Your Distrust Is Rational (And What Changed)

Tuskegee, informed consent, and the road that got us here. Plain Talk + The Informed. Foundations.

Justin Yamashita
Justin Yamashita

New to Root to Rx?

Start with the Skeptic’s Toolkit. 10 questions that separate real science from noise. Free.

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Root to Rx

Clinical research, explained without the spin. Because understanding matters.

The views expressed on Root to Rx are my own and do not represent the views or positions of my employer, or any affiliated organization.

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