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Root to Rx
Oliver Buchannon
Justin Yamashita

Benchtop, site, CRO. Three levels of basic and clinical research, explained without spin

The Informed

R2Rx Issue 020 The Informed: Artemisinin, and Who Actually Paid for It

Aug 27, 2026

•

6 min read

R2Rx Issue 020 The Informed: Artemisinin, and Who Actually Paid for It

A government funded the search. A lab made the part anyone could own. Neither of those is a cover-up.

Justin Yamashita
Justin Yamashita

Plain Talk

R2Rx Issue 020 Plain Talk: Nobody Can Own Ginger

Aug 26, 2026

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8 min read

R2Rx Issue 020 Plain Talk: Nobody Can Own Ginger

The real reason natural remedies don't get trials has nothing to do with hiding anything.

Justin Yamashita
Justin Yamashita

The Root Room

R2Rx Issue 020 The Root Room: The Freezer Nobody's Hiding

Aug 24, 2026

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7 min read

R2Rx Issue 020 The Root Room: The Freezer Nobody's Hiding

Marisol asked a fair question in a grocery aisle about a cleanse her aunt already bought for her mother. The answer is in a room she has never heard of.

Justin Yamashita
Justin Yamashita

Vaccines

+1

R2Rx Issue 019 The Informed: What the Monitoring Actually Shows

Aug 20, 2026

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6 min read

R2Rx Issue 019 The Informed: What the Monitoring Actually Shows

Two watchtowers, three diseases, and four documented reasons the claim keeps working anyway.

Justin Yamashita
Justin Yamashita

Vaccines

+1

R2Rx Issue 019 Plain Talk: The Disease You Were Never Allowed to Picture

Aug 19, 2026

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7 min read

R2Rx Issue 019 Plain Talk: The Disease You Were Never Allowed to Picture

The claim needs one thing to work, and it isn't a study. It's your memory.

Justin Yamashita
Justin Yamashita

The Root Room

+1

R2Rx Issue 019 Root Room: Two Ways That Dinner Could Have Gone

Aug 17, 2026

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7 min read

R2Rx Issue 019 Root Room: Two Ways That Dinner Could Have Gone

Same table, same grandmother, same facts. One version ends with her sharing four more posts.

Justin Yamashita
Justin Yamashita

Big Wellness

+2

R2Rx Issue 018 The Verdict: Two Claims Go on Trial

Aug 14, 2026

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4 min read

R2Rx Issue 018 The Verdict: Two Claims Go on Trial

The "you'd be a guinea pig" claim comes back FEAR BAIT. The "there's no way to find one" claim comes back DEAD END.

Justin Yamashita
Justin Yamashita

Clinical Trials

+1

R2Rx Issue 018 The Informed: How the Trial Registry Actually Works

Aug 13, 2026

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4 min read

R2Rx Issue 018 The Informed: How the Trial Registry Actually Works

The list was never secret. For most of history, though, it also barely existed.

Justin Yamashita
Justin Yamashita

Clinical Trials

+1

R2Rx Issue 018 Plain Talk: The Last Resort That Isn't

Aug 12, 2026

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4 min read

R2Rx Issue 018 Plain Talk: The Last Resort That Isn't

The claim: trials are for people with nothing left to try. The catch: nobody who says that has actually looked.

Justin Yamashita
Justin Yamashita

Clinical Trials

+1

R2Rx Issue 018 Root Room: The Husband Who Almost Didn't Let Her Look

Aug 11, 2026

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4 min read

R2Rx Issue 018 Root Room: The Husband Who Almost Didn't Let Her Look

A newly diagnosed woman wants to look at a clinical trial. Her husband, scared and quoting Monday's villain almost word for word, wants the door shut.

Justin Yamashita
Justin Yamashita

Clinical Trials

+1

R2Rx Issue 018 Black Box Warning: The Door They Keep Telling You Is Closed

Aug 10, 2026

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3 min read

R2Rx Issue 018 Black Box Warning: The Door They Keep Telling You Is Closed

Clinical trials aren't a last resort. They're a door most people are never shown.

Justin Yamashita
Justin Yamashita

Big Wellness

+3

R2Rx Issue 017 The Verdict: Two Claims Go on Trial

Aug 7, 2026

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5 min read

R2Rx Issue 017 The Verdict: Two Claims Go on Trial

The "it's natural and safer" claim comes back FEAR BAIT. The "real science backs it" claim comes back NOT YET.

Justin Yamashita
Justin Yamashita

Big Wellness

+3

R2Rx Issue 017 The Informed: BPC-157 and the Blank-Label Paradox

Aug 6, 2026

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5 min read

R2Rx Issue 017 The Informed: BPC-157 and the Blank-Label Paradox

Same fear, no receipt: what we actually know, and don't, about BPC-157.

Justin Yamashita
Justin Yamashita

Big Wellness

+3

R2Rx Issue 017 Plain Talk: The 'Natural Alternative' With No Trial Behind It

Aug 5, 2026

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4 min read

R2Rx Issue 017 Plain Talk: The 'Natural Alternative' With No Trial Behind It

The claim: it's safer because it's natural. The catch: nobody ever checked.

Justin Yamashita
Justin Yamashita

The Root Room

+3

R2Rx Issue 017 Root Room: The Room Where They Argued About Peptides

Aug 4, 2026

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6 min read

R2Rx Issue 017 Root Room: The Room Where They Argued About Peptides

The FDA advisory council spent two days deciding this exact question recently. Here's what that argument sounded like.

Justin Yamashita
Justin Yamashita

Big Wellness

+3

R2Rx Issue 017 Black Box Warning: The Vial With No Warning Label

Aug 3, 2026

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3 min read

R2Rx Issue 017 Black Box Warning: The Vial With No Warning Label

People will quote a drug's side effect leaflet to refuse it, then inject a peptide that has no leaflet at all.

Justin Yamashita
Justin Yamashita

Open Site File

The Open Site File | Issue 5 | The Investigational Product

Jul 31, 2026

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4 min read

The Open Site File | Issue 5 | The Investigational Product

How a clinical research site actually runs, behind the locked door.

Justin Yamashita
Justin Yamashita

Big Wellness

+2

R2Rx Issue 016 The Verdict: Two Claims Go on Trial

Jul 31, 2026

•

4 min read

R2Rx Issue 016 The Verdict: Two Claims Go on Trial

Berberine comes back oversold. Red yeast rice comes back misbranded.

Justin Yamashita
Justin Yamashita

Big Wellness

+2

R2Rx Issue 016 The Informed: Same Molecule, Two Rulebooks

Jul 30, 2026

•

5 min read

R2Rx Issue 016 The Informed: Same Molecule, Two Rulebooks

The evidence underneath this week's two claims, with references.

Justin Yamashita
Justin Yamashita

Big Wellness

+2

R2Rx Issue 016 Plain Talk: The Supplement That Wants to Be a Drug

Jul 29, 2026

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5 min read

R2Rx Issue 016 Plain Talk: The Supplement That Wants to Be a Drug

Nature's Ozempic, and the bottle that's secretly a statin.

Justin Yamashita
Justin Yamashita

The Root Room

+2

R2Rx Issue 016 Root Room: The Room That Actually Checks

Jul 28, 2026

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6 min read

R2Rx Issue 016 Root Room: The Room That Actually Checks

We take Jay's bottles to the one room that actually checks what's inside.

Justin Yamashita
Justin Yamashita

Big Wellness

+2

R2Rx Issue 016 Black Box Warning: The Supplement That's Just a Drug in a Costume

Jul 27, 2026

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3 min read

R2Rx Issue 016 Black Box Warning: The Supplement That's Just a Drug in a Costume

Your "natural" cholesterol fix is a statin in disguise.

Justin Yamashita
Justin Yamashita

The Root Room

+5

Your Week at Root to Rx: The Five Tracks

Jul 26, 2026

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2 min read

Your Week at Root to Rx: The Five Tracks

One story a day now, and a one-minute way to set what lands in your inbox.

Justin Yamashita
Justin Yamashita
The Open Site File | Issue 4 | The Enrollment Question

Jul 24, 2026

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4 min read

The Open Site File | Issue 4 | The Enrollment Question

What enrollment looks like

Justin Yamashita
Justin Yamashita

Big Wellness

+2

Root to Rx Issue 015 - Plain Talk: The Longest List on Television

Jul 23, 2026

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5 min read

Root to Rx Issue 015 - Plain Talk: The Longest List on Television

The scary list at the end of a drug ad is a receipt. Here is who signed it.

Justin Yamashita
Justin Yamashita
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Root to Rx

Clinical research, explained without the spin. Because understanding matters.

The views expressed on Root to Rx are my own and do not represent the views or positions of my employer, or any affiliated organization.

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